Epredia™ Lab Vision™ p53 Rabbit Monoclonal Antibody (Clone SP5)
Employ part of a comprehensive antibody portfolio with the Epredia™ p53, Rabbit Monoclonal Antibody (Clone SP5). Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.
Marca: Epredia™ RM-9105-R7
Detalles adicionales : Peso : 0.01200kg
Descripciónp53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Host Species: Rabbit
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant human full-length wild type p53 protein
Molecular Weight: 53kDa
Positive Control: MDA-231 cells, Colon CA
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
|Recombinant human full-length wild type p53 protein|
|Cancer and Tumor Biology|