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p170/p-Glycoprotein/MDR Ab-2 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results with the Epredia™ p170/p-Glycoprotein/MDR Ab-2, Mouse Monoclonal Antibody.
Marca: Epredia MS-660-PABX
Detalles adicionales : Peso : 0.00180kg
Descripción
Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.Host Species: Mouse
Clone: F4
Isotype: IgG1
Species Reactivity: Human, Chinese Hamster. Does not react with mouse. Others not known.
Epitope: Extracellular amino terminal half. This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to p-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of p-glycoprotein, respectively.
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Molecular Weight: 170kDa
Positive Control: Drug-resistant cells, Kidney or breast CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Flow Cytometry (Fixed cells only)
Note:
USA: RUO; Int'l: RUO
Especificaciones
| p170/p-Glycoprotein/MDR Ab-2 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 200 μL | |
| Cancer and Tumor Biology | |
| Hamster, Human | |
| IgG1 |
| Immunofluorescence, Western Blot | |
| F4 | |
| Unconjugated | |
| Human and hamster drug-resistant viable cells followed by crude plasma membranes | |
| RUO | |
| Primary | |
| Concentrated |