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Epredia™ Lab Vision™ p130/Rb2 Ab-2 Mouse Monoclonal Antibody with BSA and azide

Take advantage of a quality product that delivers accurate results with the Epredia™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.

Marca:  Epredia™ MS-866-PABX

Detalles adicionales : Peso : 0.00180kg

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Código de producto. 12692487

  • 640.00€ / 200 microlitros

Envío estimado: 29-06-2021

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Descripción

Descripción

Two retinoblastoma-related proteins, p107 and pRb2/p130 are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105). Like pRb they bind transforming proteins of DNA tumor viruses through a particular region called the “pocket domain”. Both proteins play a fundamental role in growth control. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.

Host Species: Mouse

Clone: 130P215; same as DCS-215

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 878-913

Immunogen: A synthetic peptide from p130 corresponding to aa 878-913

Molecular Weight: 130kDa

Positive Control: A427 cells, Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

p130/Rb2 Ab-2
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG1
RUO
Primary
Monoclonal
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
130P215; same as DCS-215
Unconjugated
Concentrated
A synthetic peptide from p130 corresponding to aa878-913
200μL
Cell Cycle
Primary
Human, Rat
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