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MMP-2 (72kDa Collagenase IV) Ab-2 Mouse Monoclonal Antibody, Epredia™

Epredia™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Marca:  Epredia MS-804-P0

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12672347

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Descripción

Descripción

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Mouse

Clone: VB3

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human native 72kDa MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Not Suitable)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

MMP-2 (72kDa Collagenase IV) Ab-2
Monoclonal
200μg/mL
Mouse
100 μL
Proteases And Inhibitors
Human
IgG2a κ
Immunofluorescence, Immunoprecipitation, Western Blot
VB3
Unconjugated
Human native 72kDa MMP-2
RUO
Primary
Concentrated
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