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Epredia™ Lab Vision™ Microphthalmia (Transcription Factor) (MiTF) Ab-2 Mouse Monoclonal Antibody, biotin labeled with BSA and azide

Ensure accurate, reproducible results in immunohistochemistry experiments with the Epredia™ Microphthalmia (Transcription Factor) (MiTF) Ab-2, Mouse Monoclonal Antibody.

Marca:  Epredia™ MS-772-PABX

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12682307

  • 535.00€ / 200 microlitros

Envío estimado: 29-06-2021

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Descripción

Descripción

Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells and bone development. The mutation of Mi causes Waardenburg Syndrome type II in humans. In mice, a profound loss of pigmented cells in the skin eye and inner ear results, as well as osteopetrosis and defects in natural killer and mast cells. There are two known isoforms of Mi differing by 66 amino acids at the NH2 terminus. Shorter forms are expressed in melanocytes and run as two bands at 52kDa and 56kDa, while the longer Mi form runs as a cluster of bands at 60-70kDa in osteoclasts and in B16 melonoma cells (but not other melanoma cell lines), as well as mast cells and heart.

Host Species: Mouse

Clone: D5

Isotype: IgG1/κ

Species Reactivity: Human and Dog. Does not react with mouse and rat. Others not known.

Epitope: N-terminal

Immunogen: N-terminal fragment of human Mi protein

Molecular Weight: 52-56kDa doublet

Positive Control: 501 Mel cells, Melanoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Microphthalmia (Transcription Factor) (MiTF) Ab-2
Monoclonal
1mg/mL
Ab Without BSA/Azide (Frozen)
Murine
IgG2a kappa
RUO
Primary
Monoclonal
Immunohistochemistry (Paraffin)
D5
Unconjugated
Concentrated
N-terminal fragment of human Mi protein
200μL
Transcription Regulation
Primary
Canine, Human
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Documentos
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