Epredia™ Lab Vision™ LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide
Recommended for a variety of techniques, Epredia™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Marca: Epredia™ MS-664-P1ABX
Detalles adicionales : Peso : 1.00000kg
DescripciónMajor vault protein (MVP) is identical to lung-resistance related protein (LRP). Its shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP. Reportedly, the lung-resistance related protein (LRP) is identical to human MVP. LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy.
Host Species: Mouse
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Molecular Weight: 104-110kDa
Positive Control: SKBR-3 cells, Breast tumors
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
- Gel Supershift
- Flow Cytometry
USA: RUO; Int'l: RUO
|LRP/MVP (Major Vault Protein) Ab-2|
|Ab without BSA/Azide (Frozen)|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells|
|Cancer and Tumor Biology|