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Epredia™ Lab Vision™ LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide

Recommended for a variety of techniques, Epredia™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Marca:  Epredia™ MS-664-P1ABX

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12671957

  • 401.00€ / 100 microlitros

Envío estimado: 01-07-2021

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Descripción

Descripción

Major vault protein (MVP) is identical to lung-resistance related protein (LRP). Its shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP. Reportedly, the lung-resistance related protein (LRP) is identical to human MVP. LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy.

Host Species: Mouse

Clone: 1032

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Molecular Weight: 104-110kDa

Positive Control: SKBR-3 cells, Breast tumors

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Gel Supershift
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

LRP/MVP (Major Vault Protein) Ab-2
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG2a kappa
RUO
Primary
Monoclonal
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1032
Unconjugated
Concentrated
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
100μL
Cancer and Tumor Biology
Primary
Human, Rat
Videos
SDS
Documentos
Certificados