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IGF-1R (α-subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ IGF-1R (α-Subunit) Ab-1, Mouse Monoclonal Antibody.
Marca: Epredia MS-641-P1
Detalles adicionales : Peso : 1.00000kg
Descripción
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.Host Species: Mouse
Clone: 24-31
Isotype: IgG1
Species Reactivity: Human. Weakly reacts with Rabbit. Does not react with rat. Pig unknown.
Epitope: aa 283-440 (exon 4-6)
Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Molecular Weight: 125kDa
Positive Control: Placenta or Breast CA
Cellular Localization: Membrane
Recommended for:
- Western Blotting (Not suitable)
- Immunoprecipitation
- ELISA
- Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA)
- Does Not Significantly Inhibit IGF-1 Binding
Note:
USA: RUO; Int'l: RUO
Especificaciones
| IGF-1R (alpha-Subunit) Ab-1 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Neuroscience | |
| Human | |
| IgG1 |
| Immunoprecipitation | |
| 24-31 | |
| Unconjugated | |
| IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA | |
| RUO | |
| Primary | |
| Concentrated |