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HER-2/c-erbB-2/neu Ab-8 Mouse Monoclonal Antibody, Epredia™
Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Epredia™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.
Marca: Epredia MS-325-P0
Detalles adicionales : Peso : 1.00000kg
Descripción
c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. The c-erbB-2 protein is overexpressed in a variety of carcinomas especially those of breast and ovary.Host Species: Mouse
Clone: e2-4001
Isotype: IgG1
Species Reactivity: Human, Mouse and Rat. Others not tested.
Epitope: Cytoplasmic domain
Immunogen: Cytoplasmic domain of recombinant human HER-2/c-erbB-2 oncoprotein
Molecular Weight: 185 kDa
Positive Control: SKBR-3 cells, or T47D cells, or Breast CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry
- Western Blotting
- Immunoprecipitation (Native and Denatured)
Note:
USA: RUO; Int'l: RUO
Especificaciones
| HER-2/c-erbB-2/neu Ab-8 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 100 μL | |
| Oncogenesis | |
| Human, Mouse, Rat | |
| IgG1 |
| Immunoprecipitation | |
| e2-4001 | |
| Unconjugated | |
| Cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein | |
| RUO | |
| Primary | |
| Concentrated |