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HER-2/c-erbB-2/neu Ab-1 Rabbit Polyclonal Antibody, Epredia™
Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Epredia™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.
Marca: Epredia RB-103-P
Detalles adicionales : Peso : 0.00100kg
Descripción
c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the proteinHost Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Monkey, Rat and Mouse. Others not tested.
Epitope: C-terminal
Immunogen: Synthetic peptide derived from C-terminus of human HER-2/c-erbB-2 protein. This sequence is identical in rat neu protein.
Molecular Weight: 185 kDa
Positive Control: SKBR-3 cells, or T47D cells, or Breast CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation
Note:
USA: RUO; Int'l: RUO
Especificaciones
| HER-2/c-erbB-2/neu Ab-1 | |
| Polyclonal | |
| 1mg/mL | |
| Rabbit | |
| 1 mL | |
| Oncogenesis | |
| Human, Mouse, Non-human Primate | |
| IgG |
| Immunoprecipitation, Western Blot | |
| Polyclonal | |
| Unconjugated | |
| Synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein. This Sequence is identical in rat neu protein. | |
| RUO | |
| Primary | |
| Concentrated |