GLUT-1 (SPM498) Mouse Monoclonal Antibody, Epredia™

Descripción

Glucose is fundamental to the metabolism in mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast. GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder, has been associated with aggressive behavior.

Host Species: Mouse

Clone: SPM498

Isotype: IgG2a/κ

Species Reactivity: Human and Rat. Others not tested.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from C-terminal of human GLUT-1

Molecular Weight: 55 kDa

Positive Control: Esophageal CA

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)