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Epredia™ Lab Vision™ Estrogen Receptor Ab-16 Rabbit Polyclonal Antibody with BSA and azide

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Marca:  Epredia™ RB-1493-P

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12672957

  • 635.00€ / 1 ml

Envío estimado: 29-06-2021

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Descripción

Descripción

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Does not react with rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of human estrogen receptor, α protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)
  • Gel Supershift (Not verified)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Estrogen Receptor Ab-16
Polyclonal
1mg/mL
Purified Ab with BSA and Azide
Rabbit
IgG
RUO
Primary
Polyclonal
Immunoprecipitation, Western Blot
Polyclonal
Unconjugated
Concentrated
A synthetic peptide derived from the C-terminus of human estrogen receptor, alpha protein
1mL
Steroids Hormones and Growth Factors
Primary
Hamster, Human
Videos
SDS
Documentos
Certificados