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Epredia™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-11 Mouse Monoclonal Antibody, 200µg/mL, BSA and azide

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments.

Marca:  Epredia™ MS-396-P1

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12691307

  • 330.00€ / 500 microlitros

Envío estimado: 01-07-2021

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Descripción

Descripción

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 199.12

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Noninhibitory)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Epidermal Growth Factor Receptor/EGFR Ab-11
199.12
Unconjugated
Murine
IgG2a
RUO
Primary
Monoclonal
Monoclonal
200μg/mL
Concentrated
Extracellular domain of human recombinant EGFR protein
500μL
EGFR Family
Primary
Human
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