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Epredia™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Marca:  Epredia™ MS-378-P

Detalles adicionales : Peso : 0.00250kg

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Código de producto. 12681237

  • 550.00€ / 1 ml

Envío estimado: 01-07-2021

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Descripción

Descripción

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6

Isotype: IgG1

Species Reactivity: Human. Not mouse and rat.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells; Skin, Placenta or Squamous cell CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Inhibitory)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Epidermal Growth Factor Receptor/EGFR Ab-10
Monoclonal
200μg/mL
Purified Ab with BSA and Azide
Murine
IgG1
RUO
Primary
Monoclonal
Immunohistochemistry (Paraffin), Immunoprecipitation
111.6
Unconjugated
Concentrated
Extracellular domain of human recombinant EGFR protein
1mL
EGFR Family
Primary
Human
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