Epredia™ Lab Vision™ Cytokeratin 5 Rabbit Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cytokeratin 5, Rabbit Monoclonal Antibody.
Marca: Epredia™ RM-2106-S
Detalles adicionales : Peso : 0.00250kg
DescripciónTwenty human cytokeratins are divided into acidic (pI<5.7) and basic (pI>6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of cytokeratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of cytokeratins as markers in cancer research and tumor identification. Point mutations in cytokeratin-5 gene may cause Epidermolysis Bullosa Simplex and Dowling-Degos disease. cytokeratin-5 is expressed in most epithelioid and biphasic mesotheliomas, thymoma, squamous and other carcinomas. It is related to cytokeratin-6.
Host Species: Rabbit
Species Reactivity: Human. Others not known.
Immunogen: A synthetic peptide corresponding to residues on the C-terminus of human CK5
Molecular Weight: 59 kDa
Positive Control: Mesothelioma
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
|A synthetic peptide corresponding to residues on the C-term of human CK5|
|Cancer and Tumor Biology|
|Culture Supernatant with Azide|