Epredia™ Lab Vision™ CD44 Std./H-CAM Ab-4 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide
Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunoprecipitation and flow cytometry experiments.
Marca: Epredia™ MS-668-P
Detalles adicionales : Peso : 0.00250kg
DescripciónCD44 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. CD44 is also known as homing cell adhesion molecule (H-CAM), Phagocytic glycoprotein-1 (PgP-1), ECM-III, HUTCH-1, or Hermes-1. CD44 has been implicated in cell migration, in lymphocyte homing, and in tumor metastasis. Ab-4 reacts with red cells pretreated with 2-aminoethylisothiouronium bromide (AET). Digestion of intact erythrocytes by trypsin treatment leaves a 50-54 kDa protein fragment attached to the membrane, while chymotrypsin leaves a somewhat similarly sized 51-56 kDa component that are recognized by Ab-4. This antibody enhances IL-2 production by CD2-transfected murine hybridoma stimulated by JY cells while it has no significant effect on IL-2 production by Jurkat cells stimulated with CD3, PMA, or CD2. Ab-4 enhances proliferation of PBL stimulated with CD2.
Host Species: Mouse
Species Reactivity: Human, Baboon and Green Monkey. Does not react with rat. Others not tested.
Epitope: Resistant to digestion by trypsin and chymotrypsin
Immunogen: Stimulated human leukocytes
Molecular Weight: 80-95 kDa
Positive Control: HUVEC or HeLa cells, tonsil or esophageal CA
Cellular Localization: Membrane
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
- Flow Cytometry
|CD44 Std./H-CAM Ab-4|
|Purified Ab with BSA and Azide|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Stimulated human leukocytes|
|Human, Non-human Primate|