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Epredia™ Lab Vision™ CD44 Std./H-CAM Ab-4 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide

Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunoprecipitation and flow cytometry experiments.

Marca:  Epredia™ MS-668-P

Detalles adicionales : Peso : 0.00250kg

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Código de producto. 12671977

  • 434.00€ / 1 ml

Envío estimado: 29-06-2021

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Descripción

Descripción

CD44 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. CD44 is also known as homing cell adhesion molecule (H-CAM), Phagocytic glycoprotein-1 (PgP-1), ECM-III, HUTCH-1, or Hermes-1. CD44 has been implicated in cell migration, in lymphocyte homing, and in tumor metastasis. Ab-4 reacts with red cells pretreated with 2-aminoethylisothiouronium bromide (AET). Digestion of intact erythrocytes by trypsin treatment leaves a 50-54 kDa protein fragment attached to the membrane, while chymotrypsin leaves a somewhat similarly sized 51-56 kDa component that are recognized by Ab-4. This antibody enhances IL-2 production by CD2-transfected murine hybridoma stimulated by JY cells while it has no significant effect on IL-2 production by Jurkat cells stimulated with CD3, PMA, or CD2. Ab-4 enhances proliferation of PBL stimulated with CD2.

Host Species: Mouse

Clone: 156-3C11

Isotype: IgG2a

Species Reactivity: Human, Baboon and Green Monkey. Does not react with rat. Others not tested.

Epitope: Resistant to digestion by trypsin and chymotrypsin

Immunogen: Stimulated human leukocytes

Molecular Weight: 80-95 kDa

Positive Control: HUVEC or HeLa cells, tonsil or esophageal CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Flow Cytometry
Especificaciones

Especificaciones

CD44 Std./H-CAM Ab-4
Monoclonal
200μg/mL
Purified Ab with BSA and Azide
Murine
IgG2a
IVD
Primary
Monoclonal
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
156-3C11
Unconjugated
Concentrated
Stimulated human leukocytes
1mL
Oncogenesis
Primary
Human, Non-human Primate
Videos
SDS
Documentos
Certificados