Epredia™ Lab Vision™ Adenovirus Type 2 and 5 Ab-5 Mouse Monoclonal Antibody, 200µg/mL, BSA and azide
Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, and immunoprecipitation experiments.
Marca: Epredia™ MS-1069-PABX
Detalles adicionales : Peso : 0.00180kg
DescripciónAdenovirus Ab-5 detects adenovirus serogroups 2 and 5. The adenovirus early gene product E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth-inhibitory effects of TGF-β. The E1A region encodes a series of related proteins (35-46kDa) with multifuctional capabilities and form a specific complex with the retinoblastoma tumor suppressor gene product (Rb protein). The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region. Several conserved regions of E1A are similar to portions of other viral oncoproteins like the HPV-16 and HPV-18 E7 and SV40 large T antigen.
Host Species: Mouse
Clone: M58 + M73
Isotype: IgG2a/κ + IgG2a/κ
Species Reactivity: Adenovirus.
Positive Control: 293 cells or adenovirus infected tissues
Cellular Localization: Nuclear.
Ab-5 is excellent for staining of formalin-fixed, paraffin-embedded tissues.
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
USA: RUO; Int'l: RUO
|Adenovirus Type 2 and 5 Ab-5|
|Ab wWithout BSA/Azide (Frozen)|
|Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|M58 + M73|