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![Invitrogen™ KIT [T670E] Recombinant Human Protein:](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
Invitrogen™ KIT [T670E] Recombinant Human Protein
KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Recombinant human KIT T670E (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
492.00€ - 7490.00€
Especificaciones
| Para utilizar con (aplicación) | Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation |
|---|---|
| Formulación | 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol |
| Peso molecular | 75.3kDa |
| Requisitos de almacenamiento | Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. |
| Alias de gen | PBT, SCFR, CD117 |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
15488953
|
Invitrogen™
PV6313 |
10μg |
492.00€
10 microgramos |
Fecha estimada de envío: 30-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
15498953
|
Invitrogen™
PV6314 |
100μg |
1678.00€
100 microgramos |
Fecha estimada de envío: 08-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
15408963
|
Invitrogen™
PV6315 |
1mg |
7490.00€
1 miligramo |
Fecha estimada de envío: 08-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Especificaciones
| Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
| 75.3kDa | |
| PBT, SCFR, CD117 | |
| Human | |
| GST Tag |
| 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
| aa 544-end | |
| Recombinant |