missing translation for 'onlineSavingsMsg'
Learn More

JUN Mouse anti-Human, Mouse, Rat, Clone: 1G6B11, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66313-1-IG-150UL

Detalles adicionales : Peso : 0.00010kg

 Ver más versiones de este producto

Código de producto. 16818075

  • 319.00€ / 150 microlitros

Envío estimado: 02-11-2021

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

This antibody is raised against a region of human JUN. Both phosphorylated (p-c-Jun) and unphosphorylated forms of c-Jun, with sizes of 42-45 kDa and 36-39 kDa, respectively are obtain in some experiments.

Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the ′leucine-zipper′ motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.
Especificaciones

Especificaciones

JUN
1G6B11
Unconjugated
JUN
Liquid
Jun
JUN Fusion Protein Ag17639
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05412, P05627, P17325
Activator protein 1, AP 1, AP1, c Jun, JUN, jun oncogene, P39, Proto oncogene c Jun, Transcription factor AP 1
Mouse
IgG1
150 μL
-20°C
Primary
16476, 24516, 3725
Videos
SDS
Documentos
Certificados