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Integrin alpha-6 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 27189-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16815465

  • 319.00€ / 150 microlitros

Envío estimado: 28-10-2021

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Descripción

Descripción

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
Especificaciones

Especificaciones

Integrin alpha-6
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P23229
CD49f, Integrin alpha 6, Integrin alpha-6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6
Rabbit
IgG
150 μL
-20°C
Primary
3655
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ITGA6
Liquid
ITGA6
Integrin alpha-6 Fusion Protein Ag25835
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Videos
SDS
Documentos
Certificados