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IDH1 Mouse anti-Human, Clone: 2A6A2, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66197-1-IG-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16817855

  • 319.00€ / 150 microlitros

Envío estimado: 02-11-2021

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Descripción

Descripción

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described.
Especificaciones

Especificaciones

IDH1
2A6A2
Unconjugated
IDH1
Liquid
IDH1
IDH1 Fusion Protein Ag19293
Protein G
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O75874
IDCD, IDH, IDH1, IDP, IDPC, NADP(+) specific ICDH, Oxalosuccinate decarboxylase, PICD
Mouse
IgG1
150 μL
-20°C
Primary
3417
Videos
SDS
Documentos
Certificados