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Macherey-Nagel™ HYDRODEX™ β-TBDAc Capillary Columns for GC

Enables many compounds to be analyzed without derivatization. Macherey-Nagel™ HYDRODEX™ β-TBDAc Capillary Columns for GC are phases with 7 β-cyclodextrin glucose units for enantiomer separation in gas chromatography. This hydrophilic phase with short polar ligants is a chemically non-bonded phase.

Marca:  Macherey-Nagel™ 723384.50

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 10427862

  • 1855.00€ / cada uno

Consúltenos : 902 239 303 
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Water as solvent is strictly forbidden for all cyclodextrin phases. It is recommended to dry the sample and dissolve it in an appropriate nonpolar solvent.



A major advantage of HYDRODEX columns are that many compounds can be analyzed without derivatization. However, for certain substances, enantioselectivity can be favorably influenced by formation of derivatives. Regioselective derivatization of the hydroxyl groups leads to phases with varying enantioselectivity, which are well suited for GC enantiomer analyses.

It is not possible to make a general prediction about which HYDRODEX™ phase could solve a given separation task. Even for compounds with small structural differences or within homologous series, the enantiodifferentiation can be quite different.

  • Base material: cyclic oligosaccharides consisting of seven β-cyclodextrin glucose units bonded through α-1,4-linkages
  • heptakis-(2,3-di-O-acetyl-6-O-t-butyldimethylsilyl)-β-cyclodextrin
  • Ligands: R2=R3=acetyl, R6=t-butyldimethylsilyl; n=2
  • Due to the high melting point of the phases, they are diluted with optimized polysiloxanes
  • Recommended for alcohols, esters, ketones, aldehydes, δ-lactones


0.4 mm
0.25 mm
Hydrodex β-TBDAc
50 m
GC Capillary Column
GC Enantiomer Separation
For isothermal operations: 220°C, For short isotherms in a temperature program: 240°C
Hydrodex β-TBDAc
1 Each