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STEMCELL Technologies Human Recombinant GDNF

Glial cell line-derived neurotrophic factor

Marca:  STEMCELL Technologies 78058

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17179461

  • 272.65€ / 10 microgramos
Fecha estimada de envío: 04-04-2024
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Descripción

Descripción

  • Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor and a member of the tumor growth factor (TGF)-beta superfamily
  • The GDNF family of growth factors also includes neurturin, persephin, and artemin, which have seven conserved cysteine residues called cysteine-knots
  • GDNF family ligands signal through binding to specific GDNF-family receptor-α (GFRα) co-receptors and activate the RET receptor tyrosine kinase
  • Four different forms of GFRα co-receptors have been characterized (GFRα 1-4); GDNF binds specifically to GFRα1 prior to forming a complex with RET (Airaksinen & Saarma)
  • GDNF, together with Human Recombinant BDNF (Catalog #78005), BrainPhys™ Neuronal Medium (Catalog #05790), and other supplements, can be used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into neurons
Especificaciones

Especificaciones

Astrocyte-derived trophic factor, ATF, ATF1, ATF2, Glial cell-derived neurotrophic factor
10 μg
Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
≥95%
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