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ACROBiosystems Human PCSK9 Protein, His Tag
en la oferta - 423.38€
Especificaciones
Número de acceso | AAI66619.1 |
---|---|
Peso molecular | 13.8 kDa and 58.1 kDa |
Fuente | Human PCSK9, His Tag (PC9-H5223) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1). |
Inmunógeno | Gln 31 - Gln 692 |
Requisitos de almacenamiento | -20°C |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
15348285
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ACROBiosystems
PC9-H5223-1MG |
1 mg |
en la oferta
1 miligramo |
N/A | Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Este artículo requiere una actualización de precios antes de ser solicitado. Solicite el precio de este artículo aquí. |
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15877427
|
ACROBiosystems
PC9-H5223-50UG |
50 μg |
423.38€
50 microgramos |
Fecha estimada de envío: 07-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
This protein carries a polyhistidine tag at the C-terminus. This protein undergoes autocatalytic cleavage to release the pro-peptide and mature chain. The pro-peptide and mature chain are associated through non‐covalent interactions and with a calculatedEspecificaciones
AAI66619.1 | |
Human PCSK9, His Tag (PC9-H5223) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1). | |
-20°C | |
PCSK9 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |
13.8 kDa and 58.1 kDa | |
Gln 31 - Gln 692 | |
PCSK9,FH3,HCHOLA3,LDLCQ1,NARC1,PC9 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>97% as determined by SDS-PAGE |