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ACROBiosystems Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag
Marca: ACROBiosystems NC4-H5253-1mg
Detalles adicionales : Peso : 0.00010kg
Descripción
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 55.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
| NP_002250.1 (NKG2A) and N/A | |
| 1 mg | |
| Ala 113 - Leu 233 (NKG2A) and Asp 57 - Ile 179 (CD94) | |
| NKG2A and CD94 | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 55.5 kDa | |
| Human NKG2A&CD94;, Mouse IgG2a Fc Tag (NC4-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) and Asp 57 - Ile 179 (CD94) (Accession # P26715-1 (NKG2A) and Q13241-1 (CD94)). | |
| -20°C | |
| NKG2A and CD94 | |
| Human | |
| 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |