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ACROBiosystems Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag

Marca:  ACROBiosystems NC4-H5253-1mg

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17186521

  • 2896.79€ / 1 miligramo
Fecha estimada de envío: 19-10-2022
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Descripción

Descripción

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 55.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_002250.1 (NKG2A) and N/A
55.5 kDa
1 mg
Ala 113 - Leu 233 (NKG2A) and Asp 57 - Ile 179 (CD94)
NKG2A and CD94
Unconjugated
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human NKG2A&CD94;, Mouse IgG2a Fc Tag (NC4-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) and Asp 57 - Ile 179 (CD94) (Accession # P26715-1 (NKG2A) and Q13241-1 (CD94)).
-20°C
NKG2A and CD94
Mouse IgG Fc Tag
Less than 0.1 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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