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Abnova™ Human JAK2 (NP_004963.1, 532 a.a. - 1132 a.a.) V617F mutant Partial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells
Used for Func, SDS-PAGE
Marca: Abnova™ P5762.5ug
Detalles adicionales : Peso : 0.02000kg
Descripción
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq]
Especificaciones
| NP_004963.1 | |
| Liquid | |
| 97kDa | |
| Baculovirus infected insect cell (Sf21) expression system | |
| SDS-PAGE Stained with Coomassie Blue | |
| Store at -80°C. Aliquot to avoid repeated freezing and thawing. | |
| JTK10 | |
| JAK2 | |
| Baculovirus | |
| GST | |
| Liquid |
| Functional Study, SDS-PAGE | |
| 3717 | |
| JAK2 (V617F) (Human) Recombinant Protein | |
| Glutathione sepharose chromatography | |
| 5 ug | |
| RUO | |
| JAK2 | |
| The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000. Substrate : Srctide. ATP: 100 µM. |
|
| Recombinant | |
| Baculovirus infected insect cell (Sf21) expression system | |
| 74% by SDS-PAGE/CBB staining |