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ACROBiosystems Human IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free

443.87€ - 4450.73€

Especificaciones

Número de acceso NP_057668.1 (IL23A) and NP_002178.2 (IL12B)
Peso molecular 19.5 kDa (IL23A) and 34.7 kDa (IL12B)
Fuente Human IL-23 A&IL-12; B Heterodimer Protein, His Tag&Tag; Free (ILB-H52W5) is expressed from human 293 cells (HEK293). It contains AA Arg 20 - Pro 189 (IL23A) and Ile 23 - Ser 328 (IL12B) (Accession # Q9NPF7-1 (IL23A) and P29460-1 (IL12B)).
Inmunógeno Arg 20 - Pro 189 (IL23A) and Ile 23 - Ser 328 (IL12B)
Requisitos de almacenamiento -20°C
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15897087
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ACROBiosystems
ILB-H52W5-1MG
1 mg
4450.73€
1 miligramo
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Fecha estimada de envío: 11-04-2024
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15807097
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ACROBiosystems
ILB-H52W5-50UG
50 μg
443.87€
50 microgramos
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Fecha estimada de envío: 11-04-2024
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Descripción

Descripción

Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Human IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free, produced by co-expression of IL-23 alpha and IL-12 beta, has a calculated MW of 19.5 kDa (IL-23 alpha) and 34.7 kDa (IL-12 beta). Subunit IL-23 alpha is fused with a polyhistidine tag at the N-ter
Especificaciones

Especificaciones

NP_057668.1 (IL23A) and NP_002178.2 (IL12B)
Human IL-23 A&IL-12; B Heterodimer Protein, His Tag&Tag; Free (ILB-H52W5) is expressed from human 293 cells (HEK293). It contains AA Arg 20 - Pro 189 (IL23A) and Ile 23 - Ser 328 (IL12B) (Accession # Q9NPF7-1 (IL23A) and P29460-1 (IL12B)).
-20°C
IL23A and IL12B
Human
PBS, pH7.4
HEK293
Cytokines and Growth Factors
19.5 kDa (IL23A) and 34.7 kDa (IL12B)
Arg 20 - Pro 189 (IL23A) and Ile 23 - Ser 328 (IL12B)
IL-23 alpha and IL-12 beta
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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