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ACROBiosystems Human IL-17 RA / CD217 Protein, His Tag

Marca:  ACROBiosystems ILA-H5222-100UG

Detalles adicionales : Peso : 0.00001kg

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Código de producto. 15887067

  • 347.90€ / 100 microgramos
Fecha estimada de envío: 09-02-2023
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Descripción

Descripción

Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_055154.3
34.3 kDa
100 µg
Leu 33 - Trp 320
CD217,CDw217,IL-17 RA,IL17R,CANDF5,hIL-17 R
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>98% as determined by SDS-PAGE
Human IL-17 RA, His Tag (ILA-H5222) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Trp 320 (Accession # Q96F46-1).
-20°C
IL-17 RA
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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