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Gibco™ Human HGF Recombinant Protein, PeproTech®
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Código de producto. 17869992
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Cantidad:
100 μg
10 μg
2 x 250 μg
250 μg
2 μg
4 x 250 μg
50 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
paquete de 2
paquete de 4
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Código de producto. Cantidad unitSize
17869992 100 μg 100 microgramos
17801743 10 μg 10 microgramos
30087501 4 x 250 μg paquete de 4
17831503 4 x 250 μg 1 miligramo
30087788 2 x 250 μg paquete de 2
17861333 250 μg 250 microgramos
17800753 2 μg 2 microgramos
17810273 2 x 250 μg 500 microgramos
17869982 50 μg 50 microgramos
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Código de producto. 17869992 Proveedor Gibco™ N.º de proveedor 10039100UG

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Recombinant Protein

100-39-1MG will be provided as 4 x 250 μg (100-39-250UG). 100-39-500UG will be provided as 2 x 250 μg (100-39-250UG). Recombinant Human HGF is an 80.0 kDa polypeptide consisting of 697 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P14210
Para utilizar con (aplicación) Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 3082
Peso molecular 80 kDa
Nombre Human HGF
Método de purificación Purified
Cantidad 100 μg
Fuente Insect cells
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen C230052L06Rik; DFNB39; Fibroblast derived tumor cytotoxic factor; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor; Hepatocyte growth factor (hepapoietin A; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; Lung fibroblast derived mitogen; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; scatter factor); SF; SF/HGF
Nombre común HGF
Símbolo de gen Hgf
Actividad biológica Determined by the dose-dependent stimulation of the proliferation of monkey 4 MBr-5 cells. The expected ED50 for this effect is 1.0-20.0 ng/ml
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia Alpha chain: QRKRRNTIHE FKKSAKTTLI KIDPALKIKT KKVNTADQCA NRCTRNKGLP FTCKAFVFDK ARKQCLWFPF NSMSSGVKKE FGHEFDLYEN KDYIRNCIIG KGRSYKGTVS ITKSGIKCQP WSSMIPHEHS FLPSSYRGKD LQENYCRNPR GEEGGPWCFT SNPEVRYEVC DIPQCSEVEC MTCNGESYRG LMDHTESGKI CQRWDHQTPH RHKFLPERYP DKGFDDNYCR NPDGQPRPWC YTLDPHTRWE YCAIKTCADN TMNDTDVPLE TTECIQGQGE GYRGTVNTIW NGIPCQRWDS QYPHEHDMTP ENFKCKDLRE NYCRNPDGSE SPWCFTTDPN IRVGYCSQIP NCDMSHGQDC YRGNGKNYMG NLSQTRSGLT CSMWDKNMED LHRHIFWEPD ASKLNENYCR NPDDDAHGPW CYTGNPLIPW DYCPISRCEG DTTPTIVNLD HPVISCAKTK QLR. Beta chain: VVNGIPTRTN IGWMVSLRYR NKHICGGSLI KESWVLTARQ CFPSRDLKDY EAWLGIHDVH GRGDEKCKQV LNVSQLVYGP EGSDLVLMKL ARPAVLDDFV STIDLPNYGC TIPEKTSCSV YGWGYTGLIN YDGLLRVAHL YIMGNEKCSQ HHRGKVTLNE SEICAGAEKI GSGPCEGDYG GPLVCEQHKM RMVLGVIVPG RGCAIPNRPG IFVRVAYYAK WIHKIILTYK VPQS.
Contenido y almacenamiento -20°C
Actividad Determined by the dose-dependent stimulation of the proliferation of monkey 4MBr-5 cells. The expected ED50 for this effect is 1.0-20.0 ng/ml.
Sistema de expresión Insect cells
Formulario Lyophilized
Grado de pureza o calidad ≥98% by SDS-PAGE gel and HPLC analyses.
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