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ACROBiosystems Human FOLR1 Protein, Strep Tag
314.52€ - 2806.40€
Especificaciones
Número de acceso | NP_057937.1 |
---|---|
Peso molecular | 27.6 kDa |
Fuente | Human FOLR1, Strep Tag (FO1-H528b) is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Met 233 (Accession # NP_057937.1). |
Inmunógeno | Arg 25 - Met 233 |
Requisitos de almacenamiento | -20°C |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
15876777
|
ACROBiosystems
FO1-H528B-250UG |
250 μg |
1076.60€
250 microgramos |
Fecha estimada de envío: 30-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
16417559
|
ACROBiosystems
FO1-H528B-1MG |
1 mg |
2806.40€
1 miligramo |
Fecha estimada de envío: 30-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
15886777
|
ACROBiosystems
FO1-H528B-25UG |
25 μg |
314.52€
25 microgramos |
Fecha estimada de envío: 30-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
This protein carries a twin strep tag at the C-terminus. The protein has a calculated MW of 27.6 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
NP_057937.1 | |
Human FOLR1, Strep Tag (FO1-H528b) is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Met 233 (Accession # NP_057937.1). | |
-20°C | |
FOLR1 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |
27.6 kDa | |
Arg 25 - Met 233 | |
FOLR-1,FBP,FOLR | |
Unconjugated | |
Strep Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |