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ACROBiosystems Human EpCAM / TROP1 Protein, Fc Tag

311.92€ - 1919.45€

Especificaciones

Número de acceso AAH14785.1
Peso molecular 53.5 kDa
Fuente Human EpCAM, Fc Tag (EPM-H5254) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Lys 265 (Accession # AAH14785.1).
Inmunógeno Gln 24 - Lys 265
Requisitos de almacenamiento -20°C
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15876657
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ACROBiosystems
EPM-H5254-100UG
100 μg
311.92€
100 microgramos
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Fecha estimada de envío: 11-04-2024
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15886657
Ver documentos Detalles de la promoción
ACROBiosystems
EPM-H5254-1MG
1 mg
1919.45€
1 miligramo
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Fecha estimada de envío: 11-04-2024
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Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.5 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

AAH14785.1
Human EpCAM, Fc Tag (EPM-H5254) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Lys 265 (Accession # AAH14785.1).
-20°C
EpCAM
Human
PBS, pH7.4
HEK293
Bio-Markers and CD Antigens
53.5 kDa
Gln 24 - Lys 265
EPCAM,TACSTD1,TROP1,CD326,DIAR5,EGP2,EGP314,EGP40,ESA,GA733-2,HNPCC8,HNPCC-8,KS1/4,KSA,M4S1,MIC18,MK1
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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SDS
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