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Invitrogen™ Human Cytokeratin 8/KRT8 ELISA Kit

Product Code. 17174423
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Product Code. 17174423 Supplier Invitrogen™ Supplier No. EH147RB

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ELISA

Human CytokeRatin 8/KRT8 quantitates human Cytokeratin 8/KRT8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cytokeratin 8/KRT8.

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number AA960620; AL022697; AU019895; C CY K2C8; CARD2; cb186; CK 8; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); Cytokeratin endo A; cytokeratin-8; Cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; hard keratin; K2C8; K8; K-8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; keratin, type II cytoskeletal 8; Keratin-8; KO; Krt-2.8; krt2-8; KRT8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no0.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8
Assay Range 0.410 to 100 pg/mL
Assay Sensitivity 0.41 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 3856
Gene Symbol KRT8
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target Cytokeratin 8
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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