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ACROBiosystems Human CD27 Ligand / CD70 Protein, Fc Tag (active trimer)

MALS verified

443.87€ - 3227.08€

Especificaciones

Número de acceso NP_001243.1
Peso molecular 74.1 kDa
Fuente Human CD27 Ligand, Fc Tag (active trimer) (MALS verified) (CDL-H5266) is expressed from human 293 cells (HEK293). It contains AA Ser 52 - Pro 193 (Accession # P32970-1) trimer Design.
Inmunógeno Ser 52 - Pro 193
Requisitos de almacenamiento -20°C
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
17196231
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ACROBiosystems
CDL-H5266-1MG
1 mg
3227.08€
1 miligramo
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Fecha estimada de envío: 11-04-2024
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17186231
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ACROBiosystems
CDL-H5266-100UG
100 μg
443.87€
100 microgramos
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»
Fecha estimada de envío: 11-04-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 74.1 kDa. The protein migrates as 130-150 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_001243.1
Human CD27 Ligand, Fc Tag (active trimer) (MALS verified) (CDL-H5266) is expressed from human 293 cells (HEK293). It contains AA Ser 52 - Pro 193 (Accession # P32970-1) trimer Design.
-20°C
CD27 Ligand
Human
Tris, Glycine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
74.1 kDa
Ser 52 - Pro 193
CD70,CD27LG,TNFSF7,TNFSF7G,CD27L
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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