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Glyoxylic acid, 50% w/w aq. soln., Thermo Scientific Chemicals
Description
Glyoxylic acid is used in Hopkins Cole reaction, which is used in the detection of tryptophan in proteins. It reacts with phenol to get 4-hydroxymandelic acid, which on further reaction with ammonia gives hydroxyphenylglycine, as a precursor to the drug amoxicillin. It is also used as a starting material for the preparation of 4-hydroxyphenylacetic acid, which is used to get atenolol. It is involved in the production of agrochemicals, aromas, cosmetic ingredient and pharmaceutical intermediate. It is also used in water purification and in the preservation of food. Further, it is employed as precursor in the synthesis of iron chelates. In addition to this, it serves as an intermediate of varnish material and dyes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Glyoxylic acid is used in Hopkins Cole reaction, which is used in the detection of tryptophan in proteins. It reacts with phenol to get 4-hydroxymandelic acid, which on further reaction with ammonia gives hydroxyphenylglycine, as a precursor to the drug amoxicillin. It is also used as a starting material for the preparation of 4-hydroxyphenylacetic acid, which is used to get atenolol. It is involved in the production of agrochemicals, aromas, cosmetic ingredient and pharmaceutical intermediate. It is also used in water purification and in the preservation of food. Further, it is employed as precursor in the synthesis of iron chelates. In addition to this, it serves as an intermediate of varnish material and dyes.
Solubility
Miscible with ethanol. Slightly miscible with ether and benzene. Immiscible with esters.
Notes
Incompatible with metals, alkalies, strong oxidizing agents and strong bases.

Specifications
Specifications
Melting Point | -93°C |
Density | 1.339 |
Boiling Point | 111°C |
Quantity | 250 g |
UN Number | UN3265 |
Solubility Information | Miscible with ethanol. Slightly miscible with ether and benzene. Immiscible with esters. |
Formula Weight | 74.04 |
Concentration or Composition (by Analyte or Components) | 50% w/w aq. soln. |
Chemical Name or Material | Glyoxylic acid |
Certificates
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
Lot Number | Certificate Type | Date | Catalog Number |
---|---|---|---|
10255052 | Certificate of Analysis | 17/05/2025 | B25149.0B,B25149.30,B25149.0I |
10251639 | Certificate of Analysis | 30/08/2024 | B25149.0B,B25149.30,B25149.0I |
10241183 | Certificate of Analysis | 10/06/2022 | B25149.0B,B25149.30,B25149.0I |
10238764 | Certificate of Analysis | 12/04/2022 | B25149.0B,B25149.30,B25149.0I |
10167826 | Certificate of Analysis | 23/11/2021 | B25149.0B,B25149.30,B25149.0I |
Safety and Handling


- Glyoxylic acid, 50% w/w aquous solution
- Danger
- Serious eye damage/eye irritation Category 1
- Substances and mixtures corrosive to metals Category 1
- Skin sensitiser Category 1
- H290-May be corrosive to metals.
- H317-May cause an allergic skin reaction.
- H318-Causes serious eye damage.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Glyoxylic acid
RUO – Research Use Only
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