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GFI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 14198-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16812734

  • 109.00€ / 20 microlitros

Envío estimado: 27-10-2021

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Descripción

Descripción

GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.
Especificaciones

Especificaciones

GFI1
0.14 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P70338, Q07120, Q99684
GFI 1, GFI1, Zinc finger protein 163, Zinc finger protein Gfi 1, ZNF163
Rabbit
IgG
20 μL
-20°C
Primary
14581, 24388, 2672
Western Blot
Unconjugated
GFI1
Liquid
Gfi1
GFI1 Fusion Protein Ag5401
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Human, Mouse
Videos
SDS
Documentos
Certificados