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GALE Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 14414-1-AP-20UL
Detalles adicionales : Peso : 0.00010kg
Descripción
This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild (′peripheral′ form) to severe (′generalized′ form). Multiple alternatively spliced transcripts encoding the same protein have been identified.Especificaciones
GALE | |
Polyclonal | |
Unconjugated | |
GALE | |
Galactowaldenase, GALE, SDR1E1, UDP glucose 4 epimerase, UDP-galactose-4-epimerase | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
114860, 2582, 74246 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P18645, Q14376, Q8R059 | |
Gale | |
GALE Fusion Protein Ag5756 | |
20 μL | |
Primary | |
Mouse, Human, Rat | |
Antibody | |
IgG |