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GALE Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 14414-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16813044

  • 109.00€ / 20 microlitros

Envío estimado: 28-10-2021

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Descripción

Descripción

This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild (′peripheral′ form) to severe (′generalized′ form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
Especificaciones

Especificaciones

GALE
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P18645, Q14376, Q8R059
Galactowaldenase, GALE, SDR1E1, UDP glucose 4 epimerase, UDP-galactose-4-epimerase
Rabbit
IgG
20 μL
-20°C
Primary
114860, 2582, 74246
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
GALE
Liquid
Gale
GALE Fusion Protein Ag5756
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human, Rat
Videos
SDS
Documentos
Certificados