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FOXL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 19672-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16819144

  • 109.00€ / 20 microlitros

Envío estimado: 02-11-2021

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Descripción

Descripción

This antibody is specific to the C-term of FOXL2.

FOXL2 is a winged helix/forkhead transcription factor that is highly conserved in human, goat, mouse, and certain aquatic species. Given its cross-species conservation, it appears to play a critical role evolutionarily, likely in ovarian differentiation in mammals and in ovarian somatic cell differentiation and in further follicle development and/or maintece. Immunohistochemical data shows that FOXL2 is a nuclear protein specifically expressed in eyelids and in fetal and adult ovarian follicular cells. It does not undergo any major posttranslational modifications. FOXL2 is also found to be associated with blepharo-phimosis/ptosis/epicanthus inverses syndrome (BPES). There are two forms of BPES. Type I BPES shows eyelid abnormal-ities that are associated with ovarian failure. In type II BPES, only eyelid defects are found. Studies have shown that FOXL2 is expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles.
Especificaciones

Especificaciones

FOXL2
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O88470, P58012
BPES, BPES1, forkhead box L2, Forkhead box protein L2, FOXL2, PFRK, PINTO, POF3
Rabbit
IgG
20 μL
-20°C
Primary
26927, 367152, 668
Western Blot
Unconjugated
FOXL2
Liquid
Foxl2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
Videos
SDS
Documentos
Certificados