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ETS1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 12118-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16819643

  • 109.00€ / 20 microlitros

Envío estimado: 02-11-2021

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Descripción

Descripción

Principal Names: c-Ets-1; v-ets erythroblastosis virus E26 oncogene homlog 1 (avian); ETS-1; EWSR2; p54; Official Gene Symbol: ETS1 Gene ID: 2113 (Human) Gene Map Locus: 11q23.3 (Human) ETS1, a 441 A.A protein, is a member of DNA-binding ETS protein family. It is a multifunctional protein consisting of an N-terminal pointed domain, a central transactivation domain and 2 auto inhibitory domains flanked on both sides of conserved C-terminal Ets domain. It interacts with factors including PEBP2alphaA, p300/CBP and mediates transactivation of Osteopontin, Presenilin-1, Stromelysin and Collagenase. It is activated by Ras/MAPK signaling and its expression is up-regulated in resting T-cells. Its activity is modulated by various factors including AP-1, Sp-1, c-myb and MafB. Sp100 activates ETS1 in nuclear bodies. It interacts with EAP1/Daxx and causes repression of MMP1 and BCL2 transactivation. It interacts with STAT6 and modulates Socs-1 expression induced by IL-4. It interacts with GATA3 and positively regulates Tax-1 dependant IL-5 expression.
Especificaciones

Especificaciones

ETS1
0.2 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P14921, P27577
ETS 1, ETS1, EWSR2, p54, Protein C ets 1
Rabbit
IgG
20 μL
-20°C
Primary
2113, 23871
Western Blot
Unconjugated
ETS1
Liquid
ETS1
ETS1 Fusion Protein Ag2127
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Videos
SDS
Documentos
Certificados