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ETS1 Mouse anti-Human, Rat, Clone: 4F2D4, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66598-1-IG-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16818625

  • 319.00€ / 150 microlitros

Envío estimado: 02-11-2021

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Descripción

Descripción

Principal Names: c-Ets-1; v-ets erythroblastosis virus E26 oncogene homlog 1 (avian); ETS-1; EWSR2; p54; Official Gene Symbol: ETS1 Gene ID: 2113 (Human) Gene Map Locus: 11q23.3 (Human) ETS1, a 441 A.A protein, is a member of DNA-binding ETS protein family. It is a multifunctional protein consisting of an N-terminal pointed domain, a central transactivation domain and 2 auto inhibitory domains flanked on both sides of conserved C-terminal Ets domain. It interacts with factors including PEBP2alphaA, p300/CBP and mediates transactivation of Osteopontin, Presenilin-1, Stromelysin and Collagenase. It is activated by Ras/MAPK signaling and its expression is up-regulated in resting T-cells. Its activity is modulated by various factors including AP-1, Sp-1, c-myb and MafB. Sp100 activates ETS1 in nuclear bodies. It interacts with EAP1/Daxx and causes repression of MMP1 and BCL2 transactivation. It interacts with STAT6 and modulates Socs-1 expression induced by IL-4. It interacts with GATA3 and positively regulates Tax-1 dependant IL-5 expression.
Especificaciones

Especificaciones

ETS1
4F2D4
Unconjugated
ETS1
Liquid
ETS1
ETS1 Fusion Protein Ag2127
Protein A
RUO
Antibody
Monoclonal
Human, Rat
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P14921, P41156
ETS 1, ETS1, EWSR2, p54, Protein C ets 1
Mouse
IgG2b
150 μL
-20°C
Primary
2113, 24356
Videos
SDS
Documentos
Certificados