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EIF3E Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 10899-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16817593

  • 319.00€ / 150 microlitros

Envío estimado: 21-10-2021

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Descripción

Descripción

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Especificaciones

Especificaciones

EIF3E
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P60228, P60229, Q641X8
eIF 3 p48, eIF3 p46, EIF3 P48, EIF3E, EIF3S6, INT6
Rabbit
IgG
150 μL
-20°C
Primary
103692906, 16341, 3646
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
EIF3E
Liquid
EIF3E
EIF3E Fusion Protein Ag1132
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
SDS
Documentos
Certificados