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![EGFR (ErbB1) [L858R] Recombinant Human Protein, Invitrogen™ 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
EGFR (ErbB1) [L858R] Recombinant Human Protein, Invitrogen™
EGFR (ErbB1) [L858R] Recombinant Human Protein
Marca: Invitrogen PV4128
Detalles adicionales : Peso : 0.05250kg
Descripción
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.Especificaciones
| NP_005219.2; L858R | |
| Cell Viability, Pharma and Biopharma, Cell Proliferation and Function, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 90.5kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| EGFR (ErbB1) L858R | |
| EGFR (ErbB1) L858R was pre-diluted in enzyme dilution buffer and assayed in 25mM HEPES (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]- γ-ATP for 10 minutes at 30°C | |
| Amino acids 668-1210: L858R | |
| 840nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1μg/mL | |
| GST Tag | |
| Kinase and inhibitors | |
| 60% by SDS-PAGE |
| 0.32mg/mL | |
| 1956, 7124 | |
| EGFR (ErbB1) [L858R] Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| EGFR (ErbB1) [L858R] Recombinant Human Protein | |
| EGF receptor (ErbB) | |
| EGFR (ErbB1) [L858R] Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Receptor tyrosine kinases |
For Research Use Only. Not for use in diagnostic procedures.