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DUSP9 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 10826-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16887463

  • 325.38€ / 150 microlitros
Fecha estimada de envío: 31-05-2022
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Descripción

Descripción

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.
Especificaciones

Especificaciones

DUSP9
Polyclonal
Unconjugated
DUSP9
dual specificity phosphatase 9, DUSP9, MAP kinase phosphatase 4, MKP 4, MKP4
Rabbit
Antigen Affinity Chromatography
RUO
1852, 75590
Antibody
IgG
Immunocytochemistry, Immunofluorescence, Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q99956
DUSP9
DUSP9 Fusion Protein Ag1259
150 μL
Primary
Human, Mouse
Liquid
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Ofertas especiales