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DOK6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Especificaciones
Antígeno | DOK6 |
---|---|
Concentración | 0.2 mg/mL |
Aplicaciones | Western Blot |
Clasificación | Polyclonal |
Conjugado | Unconjugated |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
16812604
|
Proteintech
14108-1-AP-20UL |
20 μL |
140.00€
20 microlitros |
Fecha estimada de envío: 13-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
16802604
|
Proteintech
14108-1-AP-150UL |
150 μL |
399.00€
150 microlitros |
Fecha estimada de envío: 13-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
DOK-6 (docking protein 6), is a novel member of the Dok-4/5 subclass of the p62 Dok family of intracellular adaptor molecules. Dok-6 is highly expressed in the developing central nervous system and is co-expressed with Ret in several locations, including sympathetic, sensory, and parasympathetic ganglia, as well as in the ureteric buds of the developing kidneys. Pull-down assays using the Dok-6 phosphotyrosine binding (PTB) domain and GDNF-activated Ret indicate that Dok-6 binds to the phosphorylated Ret Tyr(1062) residue. Moreover, ligand activation of Ret resulted in phosphorylation of tyrosine residue(s) located within the unique C terminus of Dok-6 predomitly through a Src-dependent mechanism, indicating that Dok-6 is a substrate of the Ret-Src signaling pathway. (Crowder RJ, Enomoto H, Yang M, Johnson EM Jr, Milbrandt J. Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth. J Biol Chem. 2004 Oct 1;279(40):42072-81. Epub 2004 Jul 30. It is also known as DOK6, HsT3226, MGC20785 or IRS. 0.Especificaciones
DOK6 | |
Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q2MHE5, Q6PKX4 | |
220164, 498898, 623279 | |
DOK6 Fusion Protein Ag5254 | |
Primary | |
-20°C | |
DOK6 |
0.2 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
docking protein 6, DOK5L, DOK6, HsT3226 | |
Dok6 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |