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DNAJB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 10838-1-AP-20UL
Detalles adicionales : Peso : 0.00010kg
Descripción
This antibody detects both isoforms of DNAJB2 with MW between 32-40 kDa.
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.Especificaciones
DNAJB2 | |
Polyclonal | |
Unconjugated | |
DNAJB2 | |
DnaJ protein homolog 1, DNAJB2, Heat shock 40 kDa protein 3, Heat shock protein J1, HSJ 1, HSJ1, HSPF3 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
3300, 56812, 689593 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.18 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P25686, Q9QYI5 | |
DNAJB2 | |
DNAJB2 Fusion Protein Ag1271 | |
20 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |