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DDR2 Recombinant Human Protein
DDR2 Recombinant Human Protein
Marca: Invitrogen PV3870
Detalles adicionales : Peso : 0.05250kg
Descripción
DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited by Gleevec.Especificaciones
| NP_006173, S642A | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 79.8kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| DDR2, TK, NTRKR3 | |
| DDR2 was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β- glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP 200μg/mL AXLtide peptide substrate (KKSRGDYMTMQIG) and trace [ 32P]-γ-ATP for 10 minutes at 30°C | |
| aa 427 to 855 | |
| 8nmoles of phosphate transferred to AXLtide peptide substrate (KKSRGDYMTMQIG) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL | |
| GST Tag | |
| Kinases and inhibitors | |
| 80% by SDS-PAGE |
| 0.45mg/mL | |
| 114294, 4921 | |
| DDR2 Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| DDR2 Recombinant Human Protein | |
| DDR kinase family | |
| DDR2 Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Receptor tyrosine kinases |
For Research Use Only. Not for use in diagnostic procedures.