Epredia™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 Mouse Monoclonal Antibody, 200µg/mL, BSA and azide
Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments.
Marca: Epredia™ MS-1248-P1
Detalles adicionales : Peso : 1.00000kg
DescripciónCFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
Host Species: Mouse
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: aa 386-412
Immunogen: Recombinant protein encoding NBF1 domain of human CFTR
Molecular Weight: 165-170 kDa
Positive Control: Pancreas
Cellular Localization: Membrane
- Western Blotting (Not verified)
USA: RUO; Int'l: RUO
|Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3|
|Recombinant protein encoding NBF1 domain of human CFTR|
|Human, Murine, Rat|