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Epredia™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 Mouse Monoclonal Antibody, 200µg/mL, BSA and azide

Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments.

Marca:  Epredia™ MS-1248-P1ABX

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12679366

  • 444.00€ / 100 microlitros

Envío estimado: 02-07-2021

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Descripción

Descripción

CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Host Species: Mouse

Clone: L12B4

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 386-412

Immunogen: Recombinant protein encoding NBF1 domain of human CFTR

Molecular Weight: 165-170 kDa

Positive Control: Pancreas

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not verified)
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3
Monoclonal
1mg/mL
Concentrated
Recombinant protein encoding NBF1 domain of human CFTR
100μL
Primary
Monoclonal
Immunofluorescence, Immunoprecipitation
L12B4
Unconjugated
Murine
IgG1
RUO
Primary
Human, Murine, Rat
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