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CHEK2 (CHK2) Recombinant Human Protein

CHEK2 (CHK2) Recombinant Human Protein

Marca:  Invitrogen PV3367

Detalles adicionales : Peso : 0.05250kg

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Código de producto. 11533447

  • 446.00€ / 10 microgramos


Fecha de envío estimada
del proveedor 22-10-2018
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Descripción

Descripción

CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
Especificaciones

Especificaciones

NP_009125
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
66kDa
80% by SDS-PAGE
–80°C
1 Each
CHEK2 (CHK2)
CHEK2 (CHK2) was pre-diluted in enzyme dilution buffer and assayed in 12.5mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL CHKtide substrate peptide (KKKVSRSGLYRSPSMPENLNRPR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
RAD53
1280nmoles of phosphate transferred to CHKtide substrate peptide (KKKVSRSGLYRSPSMPENLNRPR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 0.42μg/mL
His Tag
0.42mg/mL
11200
CHEK2 (CHK2) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
CHEK2 (CHK2) Recombinant Human Protein
Kinase assay
Baculovirus
CHEK2 (CHK2) Recombinant Human Protein
Human
Videos

For Research Use Only. Not for use in diagnostic procedures.