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Invitrogen™ CDK5 Recombinant Human Protein, Inactive

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Recombinant full-length human CDK5 was expressed in E. coli cells using a N-terminal GST tag.

Marca:  Invitrogen™ PV6301

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15451214

  • 362.00€ / 10 microgramos


Fecha de envío estimada
del proveedor 08-05-2019
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Descripción

Descripción

The active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Especificación

Especificación

Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma
59.6kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Kinase Assay
Yes
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
10μg
PSSALRE
Human
GST Tag
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