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CDK1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

140.00€ - 399.00€

Especificaciones

Antígeno CDK1
Concentración 0.13 mg/mL
Aplicaciones Western Blot
Clasificación Polyclonal
Conjugado Unconjugated
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
16817363
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Proteintech
10762-1-AP-20UL
20 μL
140.00€
20 microlitros
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Fecha estimada de envío: 17-04-2024
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16807363
Ver documentos Detalles de la promoción
Proteintech
10762-1-AP-150UL
150 μL
399.00€
150 microlitros
Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío: 17-04-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

CDK1 (CDC2, P34CDC2) is a member of the Ser/Thr protein kinase family. CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDK1 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of CDK1 also play important regulatory roles in cell cycle control. Destruction of cyclin B during metaphase results in inactivation of CDK1, allowing mitotic exit and cell division. CDK1 also contributes to the control of DNA replication and can be inhibited by several transcriptional targets of p53, such as p21WAF. The ability of CDK1 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr15 in cdc2. Research studies have shown that expression of CDK1 in the brain has been linked to both neurogenesis and apoptosis. In vertebrates, multiple cyclins like CDK1 have been identified, including a total of eight such regulatory proteins in mammals. Alternatively spliced transcript variants encoding different isoforms of CDK1 have been found.
Especificaciones

Especificaciones

CDK1
Western Blot
Unconjugated
Rabbit
Human
P06493
983
CDK1 Fusion Protein Ag1183
Primary
-20°C
CDK1
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CDC2, CDC28A, CDK1, Cell division protein kinase 1, Cyclin dependent kinase 1, p34 protein kinase
CDK1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documentos

Documentos

Product Certifications